(West Chester, Ohio) With more than 100 years of combined service to the customer, institutional and industrial chemical markets, Pilot Chemical Company and its subsidiary Mason Chemical Company are pleased to announce the expansion of its peracetic acid products to meet the growing demand for effective antimicrobial products for a diverse range of industries. These industries range from food protection, janitorial, oil & gas, commercial laundry, industrial water treatment and pulp and paper. The rise in the demand for peracetic acid products can be attributed to two basic needs:
- An antimicrobial technology capable of high-level disinfection
- An antimicrobial technology with a better environmental profile than the currently available antimicrobial technologies
With the introduction of Maguard 5626, in late 2011 Mason Chemical provided a new disinfectant tool to the cleaning product industry to respond the growing threat from “difficult to kill” pathogens like Clostridium difficile (C. diff), Norovirus, Canine Parvovirus and other pathogens requiring a higher-level disinfection (1).
Maguard 5626 and Maguard 1522 are the two products that compose the Disinfectant/Sanitizer group. Both products effectively disinfect Mycobacterium bovis, the surrogate for Tuberculosis (Tb), which distinguishes these products from ordinary base disinfectants. Beside Tb, these two products have proven effectiveness against a variety of pathogenic bacteria, fungi and viruses including: antibiotic resistant bacteria like MRSA; blood borne pathogens such as HIV, Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Coronavirus; Norovirus; and Candida.
Further evidence of the extensive disinfectant capabilities of the new Disinfectant/Sanitizer group is the listing of the Maguard 5626 on eight of the fourteen, “Selected (3) EPA-Registered Disinfectants” lists that identifies specific EPA registered disinfectant products that have been tested and been found to be effective against various pathogens. Each list is numbered with a letter and contains the name and the registration number of the disinfectant product that have been tested and found effective against the specific pathogen(s). For example, recently EPA has received a lot of attention for the N List of products, “Disinfectants for Use Against SARS-CoV-2.” Disinfectants included on this list have been qualified by EPA because the product has been tested and found effective against one of several viruses including Human Coronavirus. Maguard 5626, and Maguard 1522 have been included on EPA List N along with thirty plus other Maquat end use products and are appropriate for use to disinfect surfaces thought to be contaminated with the SARS-CoV-2 virus.
Recently, EPA created a fourteenth Selected (3) EPA-Registered Disinfectants list. This new list is for disinfectant products that have been tested and found effective against Candida auris, a fungus that presents a serious global health threat. The US CDC (16) is concerned about C. auris for three main reasons: multidrug-resistant, difficult to identify, outbreaks in healthcare facilities have been on the rise. Maguard 5626 is being added to this new list as this product has been tested and found effective against this potentially deadly pathogen, Candida auris.
Out of all the Selected EPA-Registered Disinfectants lists; List K, (EPA’s Registered Antimicrobial Products Effective against Clostridium difficile Spores) stands out as one of the most vital because of the high number of Clostridium difficile (C. diff) infections (14) and is one of the most difficult pathogens to disinfect. Maguard 5626 has been included on EPA’s List K because it is one of the few disinfectant products that has been tested and found effective against Clostridium difficile. Maguard 5626 and its more concentrated group product, Maguard 1522, provide users with a greater number of, “hard to kill” claims than are found in most base hospital grade disinfectants.
Another area that is threaten by these, “difficult to kill” pathogens are animal premises like veterinary clinics, kennels, barns, stables, and other animal quarters. Like human pathogens, there are some animal pathogens that are difficult to disinfectant and require a higher-level disinfectant to eradicate these difficult to kill pathogens. Canine Parvovirus is an example of a difficult to kill animal pathogen that infects dogs. Canine Parvovirus can cause debilitating sickness and often results in death in dogs. Canine Parvovirus requires a higher-level disinfectant like Maguard 5626 to disinfectant and eradicate this virus. A Maguard Disinfectant/Sanitizer product, when used as part of a maintenance program, could help to reduce number of these outbreaks.
Another special advantage to the Maguard peracetic acid products is its favorable environmental profile. Peracetic acid is readily biodegradable (15). Environmental fate studies have demonstrated rapid degradation in water and soil within 96 hours. After peracetic acid does its job of disinfecting it decomposes into acetic acid (vinegar), water and oxygen. Maguard and MaShield products decomposition products are viewed as (6) benign and more environmentally friendly than competing antimicrobial technologies.
Pilot Chemical Company’s expansion of its peracetic acid product portfolio now includes three product groups under its Mason Chemical subsidiary:
- Disinfectant/Sanitizers – intended for applications where a higher-level disinfectant is needed.
- Sanitizers – intended for use as a, “sanitizer” for food contact surfaces and/or laundry.
- Direct Food Contact – are FDA (7) Food Contact Substances that are allowed to be used directly on various foods like: fish, meats, poultry, seafood, fruits and vegetables.
Maguard 15A and Maguard 5322N compose the two products for the Sanitizers group. These two products are intended for applications where sanitizing is desired over disinfection. Maguard 5322N is excellent tool for clean-in-place applications where a food contact sanitizer is needed like in dairies, breweries and/or wineries. Maguard 5322N (11) is composed of 5.3 % peracetic acid, 22% hydrogen peroxide and augmented with 8.4% nitric acid to aid in the removal of calcium deposits. Calcium deposits can serve as a base for biofilm formation that insulate bacteria from an ordinary cleaning process. Maguard 5322N would be an ideal last step in the cleaning, sanitizing and removing calcium deposits from pipes serving these establishments.
Maguard 15A is a versatile sanitizer as it has uses as a food contact sanitizer, laundry sanitizer, and as a biocide for oil & gas, water treatment, wastewater, agriculture, and horticulture. Maguard can be used to sanitize a variety of food contact surfaces in food processing facilities, restaurants and other food service establishments. In addition, Maguard 15A can be used as a laundry sanitizer in commercial laundries that service lodging, healthcare and other institutional facilities After Maguard 15A does its job in preventing microbes from fouling in these applications; it degrades into benign components of water, acetic acid (vinegar) and oxygen. Maguard 15A can be an essential component building in a reliable process free from the interference of microbes in these applications.
Versatility is another key feature for the Maguard peracetic acid products. Maguard 5626 and Maguard 1522 provide robust disinfection against a broad spectrum of pathogens, are capable sanitizing food contact surfaces like countertops, dishes, glassware and can be directly applied on post-harvest fruits and vegetables (as raw agricultural commodities) to control the growth of non-pathogenic microorganisms and extend the shelf life of these treated foods. This kind of versatility suggest uses in areas where food is either prepared or served like cafeterias, convenience stores, restaurants, and/or supermarkets.
The MaShield 15DS and MaShield 22DS compose the company’s third group of peracetic acid products, Direct Sanitizers. These products can be applied directly to other foods in addition to fruits and vegetables like fish, meat, poultry and seafood. Both products are sanctioned by the US FDA as “Food Contact Substances” and have received the appropriate FDA Food Contact Numbers. The US Department of Agriculture (USDA) has sanctioned both products for use for on-line and off-line processing of poultry. When MaShield 15DS and MaShield 22DS are used according to their label directions, they can be an effective tool to reduce the threat from food borne pathogens and extend the shelf life of the treated foods.
In summary, Pilot Chemical and its subsidiary Mason Chemical Company have launched several new peracetic acid-based products to meet the needs of industry for better disinfectant tools that provide robust antimicrobial activity with a favorable environmental profile. Unlike many other options currently available, these products provide a unique combination of high-level disinfection and the benefits of an environmentally favorable profile.
These two characteristics are propelling Maguard and MaShield products into a variety of industries and applications.
Outlined below is a chart summarizing the company’s new peracetic acid product portfolio:
|Maguard 5626||EPA Reg. No. 10324-214||PAA 5.9%; H2O2 27%||High level disinfection (Tb effective) Healthcare, Animal premise|
|Maguard 1522||EPA Reg. No. 10324-230||PAA 15%; H2O2 22%||High level disinfection (Tb effective), Healthcare, Animal premise|
|Maguard 5322N||EPA Reg. No. 10324-232||PAA 5.3%; H2O2 22% (8.4 % Nitric)||Sanitizer/CIP Dairy, Breweries and wineries|
|Maguard 15A||EPA Reg. No. 10324- 231||PAA 15%; H2O2 10%||Food Contact Sanitizer, Laundry Sanitizer, Biocide for agriculture, oil & gas,|
|MaShield 15DS||FDA – Food Contact Substance||PAA 15%; H2O2 10%||Antimicrobial Solution for fish, poultry, meat, seafood, fruit and vegetables|
|MaShield 22DS||FDA – Food Contact Substance||PAA 22%; H2O2 5%||Antimicrobial Solution for fish, poultry, meat, seafood, fruit and vegetables|
- A Rational Approach to Disinfection and Sterilization https://www.cdc.gov/infectioncontrol/guidelines/disinfection/rational-approach.html
- Identifying And Using Hospital-Grade Disinfectants https://www.cleanlink.com/hs/article/Identifying-And-Using-Hospital-Grade-Disinfectants–16318
- Selected EPA-registered Disinfectants https://www.epa.gov/pesticide-registration/selected-epa-registered-disinfectants
- List K: EPA’s Registered Antimicrobial Products Effective against Clostridium difficile Spores https://www.epa.gov/pesticide-registration/list-k-epas-registered-antimicrobial-products-effective-against-clostridium
- Peracetic acid (Wikipedia) https://en.wikipedia.org/wiki/Peracetic_acid
- Disinfection, Sterilization, and Control of Hospital Waste William A. Rutala, David J. Weber, in Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (Eighth Edition), 2015 https://www.sciencedirect.com/topics/medicine-and-dentistry/peracetic-acid
- Packaging & Food Contact Substances (FCS) https://www.fda.gov/food/food-ingredients-packaging/packaging-food-contact-substances-fcs
- Maguard 5626 EPA stamped label
- Maguard 1522 EPA stamped label
- Maguard 15A stamped label
- Maguard 5322N Mason Chemical Safety Data Sheet
- Maguard 5322N EPA stamped label
- Influence of calcium in extracellular DNA mediated bacterial aggregation and biofilm formation. Das T1, Sehar S2, Koop L1, Wong YK1, Ahmed S3, Siddiqui KS4, Manefield M1. https://www.ncbi.nlm.nih.gov/pubmed/24651318
- CLOSTRIDIUM DIFFICILE: ONE OF THE MOST DIFFICULT HEALTH ACQUIRED INFECTIONS TO ERADICATE http://blog.pilotchemical.com/clostridium-difficile-one-of-the-most-difficult-health-acquired-infections-to-eradicate/
- Regulation (EU) No 528/2012 concerning the making available on the market and use of biocidal products, Evaluation of active substances, Assessment Report, Peracetic Acid. https://www.echa.europa.eu/documents/10162/8a848101-7853-2672-be2e-49a5475a0c64
- Candida auris, CDC Fact Sheet https://www.cdc.gov/fungal/candida-auris/index.html